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Biochemistry and Molecular Biology

Faculty Program Interests

 

Bruce Bowler

Bruce Bowler

Professor

bruce.bowler@umontana.edu

Biochemistry & Biophysics

Chemistry

Protein folding, conformationally-gated electron transfer and structural biology of cytochromes.

 

Stephen Lodmell

J. Stephen Lodmell

Professor

stephen.lodmell@umontana.edu

Cellular, Molecular & Microbial Biology

Biochemistry & Biophysics

The roles RNA structure and RNA-protein interactions in the regulation of viral replication and gene expression.

 

Michele Mcguirl

Michele McGuirl

Professor

michele.mcguirl@umontana.edu

Cellular, Molecular & Microbial Biology

Biochemistry & Biophysics

Prion protein aggregation and electron transfer through tyrosyl radicals.

 

Edward Rosenberg

Edward Rosenberg

Professor

ed.rosenberg@umontana.edu

Chemistry

Design and development of new silica polyamine composite materials; functionalization of DNA and proteins using trinuclear metal clusters; development of lifetime tunable metal based probes for studying the dynamics of biomacromolecules.

 

Sandy Ross

J.B. Alexander (Sandy) Ross

Professor

sandy.ross@umontana.edu

Biochemistry & Biophysics

Chemistry

Use of ensemble-average and single-molecule fluorescence to investigate the relationship between biological function and structural dynamics in protein-protein and protein-membrane interactions.

 

Scott Samuels

Scott Samuels

Professor

scott.samuels@umontana.edu

Cellular, Molecular & Microbial Biology

Biochemistry & Biophysics

Borrelia molecular biology and biochemistry

 

Valeriy Smirnov

Valeriy Smirnov

Assistant Professor

valeriy.smirnov@umontana.edu

Biochemistry & Biophysics

Chemistry

Mechanisms of metalloenzymes, characterization of reactive intermediates, activation of dioxygen and organic substrates during enzyme catalysis.

 

Kent Sugden

Kent Sugden

Professor

kent.sugden@umontana.edu

Biochemistry & Biophysics

Chemistry

Mechanism of interaction of metal complexes, particularly chromium, with biomolecules that can lead to the formation of genetic aberrations such as mutations, cancer and toxicity.

Recent publications related to Biochemistry and Molecular Biology from UM Faculty:

New methods for functionalizing biologically important molecules using triosmium metal clusters. Rosenberg E, Kumar R. Dalton Trans. 2012 Jan 21;41(3):714-22. doi: 10.1039/c1dt11173f. Epub 2011 Oct 20. PMID: 22011847

Mutation of trimethyllysine 72 to alanine enhances His79-heme-mediated dynamics of iso-1-cytochrome c. Cherney MM, Junior CC, Bowler BE. Biochemistry. 2013 Feb 5;52(5):837-46. doi: 10.1021/bi301599g. Epub 2013 Jan 23. PMID: 23311346

Dissociation of recombinant prion protein fibrils into short protofilaments: implications for the endocytic pathway and involvement of the N-terminal domain. Qi X, Moore RA, McGuirl MA. Biochemistry. 2012 Jun 5;51(22):4600-8. Epub 2012 May 23. PMID: 22591453

Characterization of RNA aptamers directed against the nucleocapsid protein of Rift Valley fever virus. Ellenbecker M, Sears L, Li P, Lanchy JM, Lodmell JS. Antiviral Res. 2012 Mar;93(3):330-9. doi: 10.1016/j.antiviral.2012.01.002. Epub 2012 Jan 10. PMID: 22252167

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