Veterinary Guidelines

Jackson Laboratory "Genetic Background: understanding its importance in mouse-based biomedical research"

Updated October 27, 2010

This resource manual outlines The Jackson Laboratory's Genetic Quality Control Program for preventing genetic contamination and its Genetic Stability Program for slowing genetic drift. Additionally, it discusses the importance of understanding substrains and genetic background in genetic research and encourages researchers to use proper nomenclature in all their research communications.

To receive a PDF copy of the manual, see the following web link:

https://secureweb.jax.org/jaxmice/literature/geneticBackground.html%20

In addition, a copy of The Jackson Larobratoy Handbook on Genetically Standardized Mice, copyright 2009 was provided to the Center for Environmental Health Sciences, the Center for Functional and Structural Neurosciences, and Laboratory Animal Resources in October 2010 to use as reference material.