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LAR Anesthetic Dosage Table

Last updated: March 2, 2012


NOTICE OF DISCLAIMER:  The information provided above is not intended to serve as a substitute for informed medical advice.  If you use any of the anesthetic tranquilizers, sedatives, anesthetics, or pain medications included in this table, seek expert advice prior to using.  The University of Montana disclaims all liability arising from the misuse of this information or the reliance on this information by any lay person, veterinarian, or non-UM entity.

Note: Most injectable drugs may be given subcutaneously (SC) in healthy mice, rats, guinea pigs, rabbits, and sheep. Onset of action may be slightly longer than IM or IP. Do NOT give ketamine IM in guinea pigs.

Drugs(s)

Mouse

Rat

Guinea Pig

Rabbit

Acepromazine

1-3 mg/kg IM, IP

1-3 mg/kg IM, IP

2-5 mg/kg IM, IP

1-5 mg/kg IM

Buprenorphine

0.05-0.1 mg/kg SC

Q6-12 hrs

0.01-0.25 mg/kg SC

Q6-12 hrs

0.05-1 mg/kg SC Q6-12 hrs

0.01-0.1 mg/kg SC Q8-12 hrs

Diazepam

5 mg/kg IP

2-4 mg/kg IP, IM

2.5-5 mg/kg IM, IP

4-10 mg/kg IM

Ketamine (rarely used alone)

50-200 IM, IP

50-100 mg/kg IM, IP

50-200 mg/kg SC

40-50 mg/kg IM

Ketamine & Xylazine

90-120 mg/kg & 8-12 mg/kg IM, IP

40-90 mg/kg & 5-10 mg/kg IM, IP

40-50 mg/kg & 5 mg/kg SC, IP

35-50 mg/kg & 5-10 mg/kg IM

Lidocaine or Bupivacaine (local analgesia)

2-3 mg/kg SC or dripped in incision; diluted 1:10

2-3 mg/kg SC or dripped in incision; diluted 1:10

2-3 mg/kg SC or dripped in incision; diluted 1:10

2-3 mg/kg SC or dripped in incision; diluted 1:10

Pentobarbital 390 mg/ml [Beuthanasia or Euthasol (for euthanasia)]

 150 mg/kg IP

150 mg/kg IP

 150 mg/kg IP

> 1 ml per 10 lbs IV

Propofol

     

7.5-15 mg/kg IV

Xylazine

4-12 mg/kg IM, IP

1-10 mg-kg IM, IP

3-5 mg/kg IM, SC

1-5 mg/kg IM

Drugs(s)

Sheep

Zebrafish

Xenopus

Bird

Acepromazine

0.05-5 mg/kg IM

   

0.5-1 mg/kg IM

Buprenorphine

0.005-0.01 mg/kg IM

Q6 hrs

   

0.01-0.05 mg/kg IM

Diazepam

0.5-1.5 mg/kg IM

   

0.5-1 mg/kg IM

Q8-12 hrs

Ketamine (rarely used alone)

20-45 mg/kg IM

1 mg/kg IV before propofol

     
 

10-50 mg/kg IM

     

Ketamine & Xylazine

     

5-50 mg/kg & 1-10 mg/kg IM

Lidocaine or Bupivacaine (local analgesia)

2-3 mg/kg SC or dripped in incision; diluted 1:10

   

1 mg/kg SC or dripped in incision; diluted 1:10

Pentobarbital 390 mg/ml [Beuthanasia or Euthasol (for euthanasia)]

> 1 ml per 10 lbs IV

   

 100 mg/kg  IV

Propofol

4-6 mg/kg IV

     

Tricaine methane sulfonate (MS-222)

 

25-100 mg/L buffered with NaHCO3

500-2000 mg/L bath buffered with NaHCO3

 

Xylazine

0.05-1 mg/kg IM

   

Use with ketamine