LAR Anesthetic Dosage Table

Last updated: July 28, 2017

NOTICE OF DISCLAIMER:  The information provided above is not intended to serve as a substitute for informed medical advice.  If you use any of the anesthetic tranquilizers, sedatives, anesthetics, or pain medications included in this table, seek expert advice prior to using in animals.  The University of Montana disclaims all liability arising from the misuse of this information or the reliance on this information by any lay person, veterinarian, or non-UM entity.

Note: Most injectable drugs may be given subcutaneously (SC) in healthy mice, rats, guinea pigs, rabbits, and sheep. Onset of action may be slightly longer than IM or IP. Do NOT give ketamine IM in guinea pigs.

Drugs(s)

Mouse

Rat

Guinea Pig

Rabbit

Acepromazine

1-3 mg/kg IM, IP

1-3 mg/kg IM, IP

2-5 mg/kg IM, IP

1-5 mg/kg IM

Buprenorphine

0.05-0.1 mg/kg SC

Q6-12 hrs

0.01-0.25 mg/kg SC

Q6-12 hrs

0.05-1 mg/kg SC Q6-12 hrs

0.01-0.1 mg/kg SC Q8-12 hrs

Diazepam

5 mg/kg IP

2-4 mg/kg IP, IM

2.5-5 mg/kg IM, IP

4-10 mg/kg IM

Ketamine (rarely used alone)

50-200 IM, IP

50-100 mg/kg IM, IP

50-200 mg/kg SC

40-50 mg/kg IM

Ketamine & Xylazine

90-120 mg/kg & 8-12 mg/kg IM, IP

40-90 mg/kg & 5-10 mg/kg IM, IP

40-50 mg/kg & 5 mg/kg SC, IP

35-50 mg/kg & 5-10 mg/kg IM

Lidocaine or Bupivacaine (local analgesia)

2-3 mg/kg SC or dripped in incision; diluted 1:10

2-3 mg/kg SC or dripped in incision; diluted 1:10

2-3 mg/kg SC or dripped in incision; diluted 1:10

2-3 mg/kg SC or dripped in incision; diluted 1:10

Pentobarbital 390 mg/ml [Beuthanasia or Euthasol (for euthanasia)]

 150 mg/kg IP

150 mg/kg IP

 150 mg/kg IP

> 1 ml per 10 lbs IV

Propofol

     

7.5-15 mg/kg IV

Xylazine

4-12 mg/kg IM, IP

1-10 mg-kg IM, IP

3-5 mg/kg IM, SC

1-5 mg/kg IM

Drugs(s)

Birds

Degu

Acepromazine

0.5-1 mg/kg IM    

Buprenorphine

0.01-0.05 mg/kg IM    

Diazepam

0.5-1 mg/kg IM

Q8-12 hrs

   

Ketamine & Xylazine

 5-50 mg/kg & 1-10 mg/kg IM    

Lidocaine or Bupivacaine (local analgesia)

1 mg/kg SC or dripped in incision; diluted 1:10

   

Pentobarbital 390 mg/ml [Beuthanasia or Euthasol (for euthanasia)]

 

100 mg/kg  IV

   

Tricaine methane sulfonate (MS-222)

 

Xylazine

Use with ketamine