Faculty, students, and research staff within the Department of Biomedical & Pharmaceutical Sciences can access state-of-the-art instrumentation needed for their research through numerous core facilities on campus.  These instrumentation cores have most often been developed through collaborative efforts involving Departments, Center and UM's Office of Research and Creative Scholarship.  In addition to fee for service operations, many of these cores also offer training to faculty and students.

Molecular Histology and Fluorescence Imaging

The purpose of the Molecular Histology side of the core is to provide researchers with theresources to prepare tissue sections for histological and immunohistochemical staining. The Fluorescence Imaging side of the core provides researchers with analyzable imagesof cells/tissues. The core contains both the equipment and the technical assistance foracquiring and analyzing images taken from both the light and confocal microscope inboth fixed tissue and live cells.

Location
Center for Environmental Health Sciences
Skaggs Building 070, 052A, 060C

Contact
Phone: (406) 243-2225
Lou Herritt, Staff Scientist

lou.herritt@umontana.edu

Fluorescence Cytometry Core

The mission of the Fluorescence Cytometry Core is to provide state of the art researchinstrumentation utilizing fluorescence labeling of cells and tissues as well as scientificexpertise to UM researchers to aid them in their efforts to unravel disease processes toultimately benefit human health.

Location
Center for Environmental Health Sciences
Skaggs Building 052

Contact
Phone: (406) 243-4974
Pam Shaw, Core Facilitator

pamela.shaw@umontana.edu

Inhalation and Pulmonary Physiology Core

The Inhalation and Pulmonary Physiology Core was established in 2010 with the missionof providing state-of-the-art technology for inhalation toxicology. Resources andexpertise are provided to investigators, laboratory personnel, and students in the use ofinhalation exposure chambers, murine pulmonary function measurements, and air samplecollection and analysis.

Location
Center for Environmental Health Sciences
Skaggs Building 061
Missoula, MT 59812

Contact
Phone: (406) 243-4579
Mary Buford, Core Manager
mary.buford@umontana.edu

Mass Spectrometry Core

The Mass Spectrometry Core Facility provides centrally managed and maintainedfacilities essential for a broad array of research in the chemical and biomedical sciencesat UM.  It contains three Mass Spectrometers: an Agilent GC/MS, a Bruker microflexMALDI-ToF Mass Spectrometer, and a Bruker-Daltonics ion trap Mass Spectrometerinterfaced with a micro-capillary LC. These instruments provide the tools needed tocharacterize the structural and dynamic properties of biological macromolecules and thecomponents of complex protein mixtures (proteomics), biopolymer sequence analysis,and small molecule characterization within environmental chemistry applications.

Location
Center for Biomolecular Structure & Dynamics
Interdisciplinary Sciences Building 106

Contact
Phone: (406) 243-6003
Dr. Earle R. Adams, Mass Spectrometry Core Director
earle.adams@umontana.edu

Molecular Computational Core Facility

The goal of the Molecular Computation Core Facility (MCCF) is to afford a variety ofmultidiscipline biomedical researchers an environment that integrates molecularmodeling and machine driven simulation tools to address fundamental research questionsthrough the development of a variety of models and simulation profiles correlated tovarious data sets.

Location
Skaggs School of Pharmacy
SB 482

Contact
Phone: (406) 243-6475
Dr. Dave Holley, Core Manager
tung-chung.mou@umontana.edu

BioSpectroscopy Core Research Laboratory

The purpose of the BioSpectroscopy Core Research Laboratory (BCRL) is to offer acentralized, shared resource for time-resolved fluorescence spectroscopy, single-moleculespectroscopy and fluorescence imaging that provides access to instruments, technologies,and services, as well as expert consultation. 

Location
Center for Biomolecular Structure & Dynamics
Chemistry Building

Contact
Phone: (406) 243-6026
Dr. Sandy Ross, Core Director
sandy.ross@umontana.edu

Magnetic Resonance Core Facility

The Magnetic Resonance Core Facility (MRCF) is operated through the Center for Biomolecular Structure and Dynamics (CBSD) and the Department of Chemistry and Biochemistry.  The goal of the core is to provide support, expertise and infrastructure to UM laboratories that use Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR) as tools for the identification of small molecules, structural elucidation of natural products and for studies on the structure and dynamics of biomolecules. The MRCF provides user training and education for all on-site users and aids in choosing and applying NMR and EPR techniques for individual researcher needs. 

Location
Department of Chemistry & Biochemistry
Chem Rm 006

Contact
Phone: (406) 243-6003
Dr. Earle R. Adams, NMR Core Director
earle.adams@umontana.edu

Macromolecular X-ray Diffraction Facility

The Macromolecular X-ray Diffraction Facility (MXDF) is operated by the Center for Biomolecular Structure and Dynamics . The goal of the core is to provide support, expertise and infrastructure to UM laboratories that use X-ray crystallography as a tool to determine the three-dimensional atomic structures of the biological macromolecules for their research projects. We offer expertise and guidance on protein expression, purification and crystallization for X-ray crystal structure analysis. We provide facilities for crystallization of macromolecules and evaluation of crystallization experiments, and measurement of diffraction data from crystals.

Location
Center for Biomolecular Structure & Dynamics
Interdisciplinary Sciences Building 106

Contact
Phone: (406) 243-6065
Dr. Tung-Chung "TC" Mou, Core Manager
tung-chung.mou@umontana.edu

Murdock DNA Sequencing Facility

The University of Montana Murdock DNA Sequencing Facility serves the needs of molecular biology researchers at universities, institutions, and government laboratories on the state and national levels. It is equipped with an Applied Biosystems Genetic Analyzer for use in DNA Sequencing and Fragment Analysis (GeneScan). The facility is housed in the Division of Biological Sciences.  Our Mission is to provide rapid, high quality DNA sequencing at very low cost to the investigators, while offering unsurpassed customer service.

Location
Division of Biological Sciences
Health Sciences 404

Contact
Phone: (406) 243-5210
Tamara Max, Lab Manager
tamara.max@mso.umt.edu

Lab Animal Resources (LAR)

The University of Montana maintains multiple vivariums on campus that are capable of housing multiple species.  The LAR is staffed by a resident veterinarian and its staff members are certified by the American Association for Laboratory Animal Science, and have had many years of experience caring for laboratory animals.  The UM Animal Care and Use Program has been accredited by the American Association for the Accreditation of Laboratory Animal Care International (AAALAC) since 1967.

Contact
Phone: (406) 243-4892
Kelly Carrick, Facility Manager
kelly.carrick@umontana.edu

Phone: (406) 552-9599
Pam Broussard, DVM, Attending Veterinarian
pamela.broussard@umontana.edu